老年直肠癌临床特征及治疗的变迁

Change of the clinical features and treatments of the elderly rectal carcinoma.

目的 了解近年来老年直肠癌临床特征及治疗的变迁。方法 回顾性分析 10年间 313例老年直肠癌患者的临床特征及治疗情况 ,对比第一个 5年和第二个 5年的临床特征及治疗方法的变迁。结果 发病年龄后延 ,误诊率降低 ,早期病例增多 ;Dixon手术增多 ,辅助治疗由简单变为综合治疗方法 ;5年生存率明显提高 ,术后的复发率明显减低。结论 老年直肠癌发病年龄后延 ,误诊率降低 ,早期病例逐渐增多 ;治疗上更趋有效、合理。

Objective To investigate the changes of the clinical features and treatments of the elderly rectal carcinoma. Methods All 313 cases of the elderly rectal carcinoma in 10 years were identified and analyzed retrospectively, compare the changes of clinical features and treatment strategy between the first five years and the later five years. Results The age of onset was delaying, the early cases and peak age of the elderly rectal carcinoma increased, but misdiagnosis rate decreased.The Dixon's operation increased and the adjuvant treatments changed from the simple therapy to the combined . In the recent 5 year, the 5-year survival rate of elderly rectal carcinoma significantly increased and the recurrence rate obviously decreased Conclusion The early cases and peak age of the elderly rectal carcinoma increased, but misdiagnosis rate decreased and the therapy became more reasonable.