子宫肌瘤患者子宫出血原因临床病理分析

Etiology of uterine hemorrhage of patient with uterine leiomyoma:an Pathologic analysis of 257 cases.

目的 探讨子宫肌瘤患者子宫出血的病理组织学基础、发生机理及临床病理关系。方法 对 2 5 7例经病理诊断为子宫平滑肌瘤的患者的临床及病理学资料进行回顾性分析。结果 2 5 7例子宫平滑肌瘤患者中 ,有子宫出血表现者占 92 % (2 38/ 2 5 7) ,其中 15 0例 (6 3% ,15 0 / 2 38)患者为子宫平滑肌瘤合并子宫内行膜病变 ,包括子宫内膜增殖症、子宫内膜息肉和子宫内膜非特异性炎症。结论 子宫平滑肌瘤合并子宫内膜病变是患者子宫出血症状的病理组织学基础。其原因与患者体内雌激素水平增高有关 ,对保守治疗患者诊断性刮宫活检明确子宫内膜病变的性质与程度对临床治疗有指导价值。

Objective To study the histpathologic base,pathogenesis and clinicopathologic relation of aterine hemorrhage in patients with aferine leiomyoma.Methods The clinical and pathologic data of 257 cases patients diagnosed uterine leiomyoma wereanalyzed.Results There were 238 cases(92%,238/257)of patients had the feature of uterine hemorrhage,and 63%(150/238)patients were uterine leiomyoma with endometrial diseases,included endometrial hyperplasia,endometrial polyp and endometritis.Conclusion Uterine leiomyoma with endometrial disease were the histopathologic base of uterine hemorrhage.Diagnosing the endometrial disease by endometrial biopsy to the pafients with conservative treatment were valuable in the clinical treatment.