期刊文献+

细胞凋亡诱导剂研究进展 被引量:4

Recent Developments of Apoptosis Inducer
下载PDF
导出
摘要 细胞凋亡诱导剂作为癌症治疗药物日益受到重视 ,并已应用于临床研究 ,是一类非常有应用前景的药物 .综述了近年来细胞凋亡诱导剂的研究状况及进展 。 The apoptosis inducers as anticancer reagents have attracted considerable attention, and now some of them have been used in clinic. They are the promising drugs toward cancer treatment. This paper reviews the recent development of apoptosis inducer with an emphasis on their structures and their structure-activity relationship.
出处 《有机化学》 SCIE CAS CSCD 北大核心 2004年第8期864-871,共8页 Chinese Journal of Organic Chemistry
基金 山东省自然科学基金重点 (No .Z2 0 0 2D0 5) 山东大学跨学科研究基金资助项目
关键词 细胞凋亡 诱导剂 抗癌药物 构效关系 结构类型 apoptosis inducer anticancer reagent structure structure-activity relationship
  • 相关文献

参考文献10

二级参考文献111

  • 1周红宁,王琪,高凤鸣.细胞凋亡研究近况[J].癌变.畸变.突变,1996,8(4):243-245. 被引量:2
  • 2XU S XU SP.-[J].药学学报,2001,36(4):269-273.
  • 3XU S XU SP.-[J].药学学报,2000,35(2):103-107.
  • 4[1]Hortobagy G N. Anthracyclines in the treatment of cancer [J]. Drugs suppl,1997,54:1-7.
  • 5[2]Arcamone F M. From the pigment of actinomycetes to third generation antitumor anthracyclines[J]. Biochimie,1998,80:201-206.
  • 6[3]Barasch D, Zipori O, Ringel I,et al. Novel anthraquinone derivatives with redox-active functional groups capable of producing free radicals by metabolism: are free radicals essential for cytotoxicity[J]. Eur J Med Chem,1999,34:597-615.
  • 7[4]Malonne H, Atassi G. DNA topoisomerase targeting drugs:Mechanism of action and perspectives[J]. Anticancer Drug,1997,8:811-822.
  • 8[5]Zagotto G, Supino R, Favivini E,et al. New 1,4-anthracene-9,10-dione derivatives as potential anticancer agents[J]. Farmaco,2000,55:1-5.
  • 9[6]Perry P J, Gowan S M, Reszka A P, et al. 1,4-and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase[J].J Med Chem,1998,41:3253-3260.
  • 10[7]Krapcho P A,Menta E,Antitumor aza-anthrapyrazoles[J].Drugs Fut,1997,22(6):641-646.

共引文献83

同被引文献79

  • 1Miao, J-Y ; Zhao, B-X ; l_,i, H-H ; Zhang, S-L ; Du ,C-Q .Acta Pharmacol Sin 2002, 23(4), 323.
  • 2Zhao, B-X ; Du, A-Y ; Miao, J-Y Zhao, K-W; Du ,C -Q .Vascular Pharmacology 2003, 40, 183.
  • 3Whaley, W M ; Govindachari, T R. Organic Reactions, Vol.6, John Wiley & Sons Inc, New York, 1957, p. 151.
  • 4Guiso, M ; Marra, C ; Cavarischia, C. Tetrahedron Lett 2001,42, 6531.
  • 5Wunseh, B ; Zott, M. Liebigs Ann Chem 1992, 39.
  • 6Cabral, L M ; Barreiro, E J. J Heterocycl Chem 1995,32, 959.
  • 7Demerson, C A ; Humber, L G ; Dobson, T A. J Med Chem 1975, 18, 189.
  • 8Demerson, C A ; Humber, L G ; Philipp, A H. J Med Chem 1976, 19, 391.
  • 9Whaley, W. M.; Govindachari, T. R. Organic Reactions, Vol.6, John Wiley & Sons Inc, New York, 1957, p. 151.
  • 10Guiso, M.; Marra, C.; Cavarischia, C. Tetrahedron Lett. 2001,42, 6531.

引证文献4

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部