舟曲大戟对映-贝壳松烯二萜研究

Ent-kaurene Diterpenoids from Euphorbia Wangii

舟曲大戟(Euphorbia wangii)为大戟属植物,化学成分未见报道。本文报道从中分离得到的4个新对映-贝壳松烯型二萜,命名为舟曲大戟素A、B、C、D。 1 舟曲大戟素A(1)

From the acetone extract of the whole plant of Euphorbia tcanyu(Euphorbiaceae), four new ent-kaurene diterpenoids, named as euphorangin A, B, C and D, were obtained. Their structures were elucidated as ent-llα-acetoxykaur-16-en-3β-ol, ent-kaur-16-en-3β, 15β-diol, ent-11α, 16α-epoxykauran-3β-ol and ent-11α, 16α-epoxykauran-3-one, respectively, on the basis of spectral methods (EIMS, IR, 1H NMR, 13CNMR, DEPT) including 2D NMR techniques (1H-1H COSY, 1H-13C COSY, 1H-1H NOESY) and chemical methods.