免疫增强剂对鲫鱼非特异性免疫功能的影响

Effects of immunostimulants on the non-specific immunity of crucian (Carassius auratus)

利用主要成分为从海洋甲壳类中提取的甲壳胺作为免疫增强剂 ,在饵料中添加不同的浓度 (0.5 %,1 %,2%) ,在0 ,10 ,20,30d时检测鲫鱼 (Carassiusauratus)的白细胞数量、白细胞吞噬功能的变化以及血清中酚氧化酶活力等免疫指标的变化。研究结果表明 ,该免疫增强剂可以提高鲫鱼血液中白细胞数量和吞噬细胞的吞噬能力 ,增强鲫鱼血清中酚氧化酶的活力 ,对鲫鱼的生长无明显影响。

To determine the effects of chitosan on innate immune response of crucian (Carassius auratus), fish were fed diets containing 0 (control), 0.5%,1%,2% chitosan for 10, 20 and 30 days. The growth rate, the number of leucocytes and the phagocytes functions together with the phenol oxidase activities were studied at each of the assayed time. The results showed that the number of leucocytes increased and the phagocytic activities were enhanced with the phenol oxidase activities were greatly increased, at the same time, no statistically significant impact on the growth rate was observed. These results showed the effects of immunostimulants on non-specific immunity of crucian enhanced with increased dose and time.