摘要
目前,将微电极植入动物脑内,采用伏安法连续监测神经递质已被公认是最有效的在体测定方法。碳纤维电极已成为活体分析中使用的主要电极,为提高其灵敏度和分辨率,电极在使用前必须经过特殊的预处理。
An simple electrochemical pretreatment has been used to active carbon fiber electrodes for in vivo determination. In rat brain, there were four well-defined semi-differential voltammet-ric peaks. The peak at 0. 36 V was combined by oxidative current of 5-HIAA and UA, 5-HIAA was about 80% and UA about 20%. The oxidation of HVA formed the peak at 0. 54 V. The concentrations in brain extracellular fluid were determined, 5-HIAA, 3×10-6 mol/L; UA, 9×10-5 mol/L and HVA 8×10-6 mol/L.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1993年第10期1374-1376,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
浙江省自然科学基金
关键词
碳纤维电极
伏安法
神经递质
尿酸
Carbon fiber electrode
Semi-differential voltammetry
Neurotransmitter
Uric acid