SO_4^(2-)/TiO_2-La_2O_3催化剂催化合成苹果酯-B

Catalytic Synthesis of Fraistone with Solid Superacid SO_4^(2-)/TiO_2-La_2O_3

制备了稀土改性固体超强酸SO42-/TiO2-La2O3催化剂。以SO42-/TiO2-La2O3为多相催化剂,对以乙酰乙酸乙酯和1,2-丙二醇为原料合成苹果酯-B的反应条件进行了研究。实验表明:固体超强酸SO42-/TiO2-La2O3是合成苹果酯-B的良好催化剂,最佳反应条件为:n(乙酰乙酸乙酯)∶n(1,2-丙二醇)=1∶1.5,催化剂用量为反应物料总质量的1.5%,环己烷为带水剂,反应时间1.5h,反应温度85℃～110℃。在上述条件下,苹果酯-B的收率可达88.6%。

Solid super acid SO_4^(2-)/TiO_2-La_2O_3 catalyst was prepared.Fraistone was synthesized from solid super acid SO_4^(2-)/TiO_2-La_2O_3. The result indicates that SO_4^(2-)/TiO_2-La_2O_3 prossesses a fairly high catalyst activity for the ketalation reaction. The factors influencing the synthesis were discussed and the best conditions were found out. The optimum conditions are: molar ratio of ethyl acetoacetate to 1,2-propylene glycol was 1∶1.5, the quantity of catalyst was equal to 1.5 % of feed stocks, and the reaction time was 1.5 h. SO_4^(2-)/TiO_2-La_2O_3 was an excellent catalyst for synthetizing fraistone and its yield can reach over 88.6 %.