滑膜肉瘤的大小初次治疗方法与其预后的关系(附41例报告)

Tumor size and primary treatment related with prognosis of synovial sarcoma

目的 :探讨滑膜肉瘤大小、初次治疗方法对其预后的影响。方法 :分析 41例滑膜肉瘤病人肿瘤的大小、初次治疗方法和预后情况。随访 2 3～ 198个月 ,平均 73个月。结果 :肿瘤直径 <5cm者与肿瘤直径 >5cm者的5、 10年生存率、复发率、转移率均有显著差异。肿瘤直径 >5cm的滑膜肉瘤病人 ,单纯手术切除与手术加放化疗后5年生存率有显著差异 ;复发率、转移率均无显著差异。结论 :( 1)肿瘤大小是影响滑膜肉瘤预后的一个重要因素。直径小于 5cm的预后好 ,肿瘤愈大 ,预后愈差。 ( 2 )初次治疗方法与其预后密切相关。

Objective:To study the prognosis of synovial sarcoma for the effect of tumor size and primary treatment.Method:Forty-one patients with synovial sarcoma were analyzed about tumor size,primary treatment and prognosis.The mean follow-up for all patients were 73 months,with a range of 23～198 months.Result:To the patients with tumor size<5cm,and >5cm,the 5-year survival rate,10-year survival rate,the rate of recurrence and distant metastases had significant difference.To the patients with tumor size>5cm,the 5-year survival rate had significant difference,while the rate of recurrence and distant metastases had no significant difference.Conclusion:(1)The tumor size is an important factor for the prognosis of synovial sarcoma.The patients with tumor size<5cm have a better survival rate.(2)The primary treatment is close related with prognosis.