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化学合成微管微丝抑制剂的研究进展 被引量:3

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摘要 微管微丝抑制剂主要与微管微丝作用 ,抑制微管微丝聚合或促进微管微丝聚合、抑制微管微丝解聚而抑制细胞分裂。以微管微丝为靶点 ,全合成新型小分子微管微丝抑制剂成为抗肿瘤药物关注的重点之一。本文就近年来化学合成的微管微丝抑制剂的结构类型、构效关系和生物活性作一综述。
出处 《国外医学(药学分册)》 2004年第3期129-133,共5页 Foreign Medical Sciences(Section of Pharmarcy)
基金 国家自然科学基金资助项目 ( 3 0 3 71673 )
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