胃癌腹腔CEA和CK-20mRNA检测的研究进展
摘要
胃癌是严重威胁我国人民健康的恶性肿瘤之一,尽管目前胃癌治疗多采用以手术为主的根治术,但是转移和复发仍然是影响胃癌患者预后的重要因素,尤其是患者腹腔的极少量游离癌细胞,往往是导致胃癌复发和微转移的基础。由于脱落的游离癌细胞数量少,浓度低,使得传统的细胞学检测方法十分有限。
参考文献18
-
1Bonenkamp JJ,Songun I, Hentmans J, et al. Prognostic value of positive cytology findings from abdominal washings in patients with gastric cancer. Br J Surg, 1996, 83:672 - 674.
-
2Abe S, Yoshimura H, Tabata H, et al.Curative resection of gastric cancer: Limitation of peritoneal lavage cytology in predicting the ourcome. J Surg Oncol, 1999,72:60 - 65.
-
3Funkai NO, Tanaka J, ltami A, et al. Detection of colorectal carcinoma cells in circulating peripheral blood by reversetranscription polymerase chain reaction targeting cytokeratin - 20mRNA. Life Sci, 1997,60:643 - 652.
-
4Castells A, Boix L, Besaa X, et al. Detection of colonic cells in peripheral blood of colorectal cancer patients by means of reverse transcriptase and polymerase chain reaction.Br J Cancer, 1998,78(10) : 1368 - 1379.
-
5Wang XH, Wang SQ. Progress on fluoresent quantitative PCR technology. Overseas Medicine Molecular Biology, 2001, 23:42 - 45.
-
6Mrras M, mikhitarian K, Waiters C, et al. Quantitative real -time RT - PCR detection of breast cancer micrometastasis using a multigene marker panel.lnt J Cancer, 2001, 93:162 - 171.
-
7Zippelius A, Kafer P, Honold G, et al.Limitations of roverse - transcriptase polymerase chain reaction analysis for detection of micro-metastatic epithelial cancer cells in bow marrow .J Clin Oncol, 1997,15:2701 - 2708.
-
8Ko Y, Grunewald E, Totzke G, et al. Limitations of revetsetranscriptase polymerase chain reaction method for the detection of carcinoembrynic antigen - poeitlve tumor cells in peripheral blood. Clin ancer Res, 1998,4:2141 - 2146.
-
9Nakanishi H, kodera Y, Torii A, et al.Detection of carcinoembryonic antigen expressing free tumor cells in peritoneal washos from patient with gastric carcinoma by polymerase chain reaction. Jpn J Cancer Ree, 1997,88(7) :687- 692.
-
10Nakanishi H, Kodera Y,Yamamura Y, et al. Molecular dlagnostic detection of free cancer cells in the peritoneal cavity of patients with gaserointestinal and gynecologic malignancies.Cancer Chemother Pharmacol, 1999,43 Suppl : s32 - 37.
-
1狄金明,吴穷,陈昌杰,章尧.CK-20在膀胱癌组织中表达的临床意义[J].肿瘤研究与临床,2004,16(3):157-159.
-
2魏杨,徐小梅.腹腔冲洗液细胞学检查对妇科肿瘤的评价分析[J].中国肿瘤临床与康复,1995,2(2):29-29.
-
3陈志新,陈佳平,彭德恕.胃癌患者与腹腔内游离癌细胞的关系[J].实用肿瘤学杂志,1995,9(1):30-31. 被引量:2
-
4胃、十二指肠[J].中国癌症防治杂志,1995(3):211-219.
-
5朱少俊,尹浩然,朱寿柱,朱正纲,薛建元,王瑞年,林言箴.胃癌与腹腔内游离癌细胞的关系[J].上海第二医科大学学报,1992,12(4):341-342. 被引量:3
-
6刘庆华,陈峻青.胃癌腹腔内游离癌细胞与预后(附100例临床报告)[J].中国实用外科杂志,1996,16(10):616-617. 被引量:29
-
7朱兆文,吴功侃,练美扬.胃癌患者腹腔内的游离癌细胞[J].肿瘤,1991,11(1):25-27. 被引量:6
-
8章琴莺,张纯海.胃癌复发的外科治疗探讨——附15例病例临床分析[J].浙江预防医学,1997,9(2):48-49.
-
9张一平,叶荣明.CT在胃癌诊断中的价值[J].浙江中西医结合杂志,2002,12(1):51-54.
-
10黄传涌,王小众,王南珍,郑兰.早期胃癌60例临床与病理分析[J].福建医科大学学报,2002,36(4):434-435. 被引量:1