拉氧头孢钠与替硝唑葡萄糖注射液配伍的稳定性考察

Study on the Stability of Latamoxef Sodium in Tinidazole Glucose Injection

目的 :考察拉氧头孢钠与替硝唑葡萄糖注射液配伍的稳定性。方法 :采用紫外分光光度法 ,考察不同时间下配伍液中两种药物的含量变化、配伍液的不溶性微粒检测及外观和pH值的变化。结果 :在室温下 ,8h内配伍液澄明 ,替硝唑含量无变化 ,拉氧头孢钠含量稍有下降 ,pH值略微变化。 结论 :拉氧头孢钠与替硝唑葡萄糖注射液可配伍使用。

Objective: To observe stability of latamoxef sodium in tinidazole glucose injection.Method: The stability of latamoxef sodium in tinidazole glucose injection at different time by UV-spectrophotometry.Result: The stability didn't change in 25℃ 8 h.Conclusion: It was stable when tinidazole glucose injection combined with Ceftezole sodium.