摘要
目的 :制备植入型丹参凝胶并建立质量控制方法。方法 :以卡波姆934为辅料制备2 %丹参凝胶 ;采用高效液相色谱法 ,以甲醇 -水 (70∶30)为流动相、检测波长为269nm测定其含量。结果 :丹参酮Ⅱ A 浓度在16 59～33 18ng/ml范围内 ,峰高与进样量线形关系良好 ,回归方程为Y=9723X—2569(n=5) ,r=0 9987。结论 :制备方法简单 ,质量稳定 。
OBJECTIVE:To prepare red sage gel for implantation and to establish a method for its quality control.METHODS:With carbamer934as vehicle,2%red sage gel was prepared;a HPLC method for the determination of tanshinone in gel was established.RESULTS:The calibration curve of tanshinoneⅡ A was linear in the concentration range of16.59～33.18ng/ml,Y=9723X—2569(n=5),r=0.9987.CONCLUSION:The preparation of red sage gel was simple,its quality was stable;the method of quality control was rapid and accurate.
出处
《中国药房》
CAS
CSCD
2004年第8期475-476,共2页
China Pharmacy
关键词
丹参
植入
凝胶剂
质量控制
red sage
implantation
gel
quality control
