阿普唑仑治疗药源性顽固性呃逆疗效观察

Therapeutic Effect of Alprazolam on Drug-induced Intractable Hiccup

目的 :评价阿普唑仑治疗药源性顽固性呃逆的疗效。方法 :在停用涉及引发呃逆的药物及积极治疗基础疾病的基础上 ,治疗组加用阿普唑仑片 ,对照组加用七叶神安片。结果 :治疗组有效率为84 4 % ,对照组有效率为66 7 % ,两组有效率具有显著性差异 (P<0 01)。结论 :阿普唑仑对药源性顽固性呃逆有较好的治疗作用 ,起效快 ,不良反应少。

OBJECTIVE:To evaluate the therapeutic effect of Alprazolam on drug-induced intractable hiccup.METHODS:The relevant drugs which induced hiccup were first discontinued and the underlying diseases were actively treated.The trial group received Alprazolam tablets and control group Qiyeshenan tablets.RESULTS:The effective rate was84.4%in trial group and66.7%in control group with significant difference(P<0.01).CONCLUSION:Alprazolam is satisfactory in treatment of drug-induced intractable hiccup with rapid onset of action and less ADRs.