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白细胞介素-6在脑梗死中的作用 被引量：6

The Effects of Interleukin-6 in Cerebral Infarction
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摘要 脑梗死是一种多因素疾病 ,其发生发展与基因的局部调控有关。白细胞介素 6是一种多效细胞因子 ,既有促炎作用又有抗炎作用 ,在脑梗死急性期的病理生理过程中起重要作用。 Cerebral infarction is a multifactorial disease. Its occurrence and development are associated with the local gene modulation. Interleukin-6 is a pleiotropic cytokine with both proinflammatory and anti-inflammatory effects. It plays an important role in the pathophysiological processes of the acute cerebral infarction.
作者 宋晓瑾 张晨
机构地区 青岛大学医学院附属医院神经内科
出处 《国外医学（脑血管疾病分册）》 2004年第7期532-535,共4页 Foreign Medical Sciences Cerebrovascular Diseases
关键词 白细胞介素-6 脑梗死 急性期 生物学效应 梗死体积 interleukin-6 ■ cerebral infarction
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献18

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  • 2Pola R, Flex A, Gaetani E, et al. Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke. Stroke, 2003, 34:8
  • 3Rauramaa R, Vaisanen SB, Luong LA, et al. Stromelysin-1 and interleukin-6 gene promoter polymorphisms are determinants of asymptomatic carotid artery atherosclerosis. Arterioscler Thromb Vasc Biol, 2000, 20:2657 -2662.
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  • 5Vila N, Reverter JC, Yague J, et al. Interaction between interleukin-6and the natural anticoagulant system in acute stroke. J Interferon Cytokine Res, 2000, 20:325 - 329.
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国外医学（脑血管疾病分册）
2004年 第7期

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