病毒性肝炎合并甲状腺功能亢进症56例临床分析

A clinical study of 56 cases of viral hepatitis amalgamating hyperthyrodism

目的 探讨病毒性肝炎合并甲状腺功能亢进症 (甲亢 )的临床特点及治疗方法。方法 对 5 6例病毒性肝炎合并甲亢患者的临床资料进行回顾性分析。结果 年龄 18～ 65岁 ,平均年龄 3 3 .5岁 ,其中男 2 6例 ,女 3 0例。所有患者均有不同程度肝炎和甲亢症状。疲乏、食欲不振占 80 .3 8%;体重减轻占 5 0 %,范围 2～ 15kg w ,较单纯肝炎多见。食欲亢进较单纯甲亢少见 ( 3 .5 %) ,恶心呕吐较单纯肝炎少见 ( 3 7.5 %)。体征以黄染最多见 ( 80 .3 6%) ,其中深度黄染占 46.67%;其次是甲状腺肿大 ( 73 .2 1%) ,其中Ⅰ～Ⅱ0 肿大占 5 7.14 %。肝功能异常程度与甲亢病情关系不明显 ,P >0 .0 5。单纯治疗肝炎对甲亢无改善 ,联合甲亢药肝功甲功均得到好转 ,并发症以感染多见。结论 对有体重明显下降而且食欲不振程度与肝功能损害程度不平行时 ,应警惕甲亢存在 ,特别是伴有甲状腺肿大、心率增快者。甲亢的轻重与肝病病情严重程度无明显相关性。除综合治疗肝炎外 。

Objective To explore the clinical characteristics and therapy methods of virus hepatitis simutanous hyperthyrodism.Methods Reviewed analysis of the clinical infamations of 56 cases with virus hepatitis simutanous hyperthyrodism.Results The age of the patients ranged from 18 to 65 years(mean:33.5 years). There were 26 males and 30 females.All patients had symptoms of hepatitis and hyperthyrodism in varying degrees.It was 80.38% of fatigue and anorexia, 50% of lossing of body weight which was 2-15kg/w and more then hepatitis.It was 3.5% of hyperorexia which was less then hyperthrodism,and 37.5% of nausea and vomit which was less then hypertitis. Yellow tinging was most common in physical signs which was 46.67% of depth.Tumefaction of thyroid gland was the second which was 73.21% and 57.14% of Ⅰ～Ⅱ 0.The relationship between the degrees of abnormal liver function and the patient’s conditions of hyperthyrodism,p>0.05.It's no improvement to hyperthyrodism when only treat hepatitis. The liver function and thyrofunction are all improved when combining antithyroid medicines. Infection is most common complication .Conclusions It was need to be vigilant the exists of hyperthyrodism when the weight looses endently, and when the degree of anorexia and that of liver function are without balance, espetially when the thyroid swells, heart rate raises.It was necessary and safe of combining antithyroid medicines with complex treatment of hepatitis.