心肌梗死患者C_(3b)受体和红细胞免疫复合物受体变化

Change of erythrocyte C_(3b) receptor and erythrocyte immunity complex receptor in the AMI patients

目的 观察急性心肌梗死患者溶栓治疗前后红细胞C3b受体 (RBC -C3bR)及红细胞免疫复合物受体(RBC -ICR)的变化。方法 与健康对照组相比 ,观察急性心肌梗死患者应用rt-PA治疗前后RBC -C3bR及RBC -ICR的变化。结果 心肌梗死急性期RBC -C3bR明显减低 (p <0 .0 1) ,RBC -ICR增高 (p <0 .0 1) ;经rt-PA治疗后14天后 ,上述免疫紊乱有所恢复。结论 急性心肌梗死患者红细胞免疫粘附功能异常 ;应用rt-PA溶栓治疗后可得到改善。

Objective To observe the changes of erythrocyte c 3b receptor(REC-C 3b R) and erythrocyte immunity complex receptor(REC-ICR) in the patients of acute myocardial infarction(AMI)before and after the thrombolytic therapy.Methods Compare REC-C 3b , and RBC-ICR of the 30 AMI patients before and after treatment of rt-PA,while 30 healthy volunteers as a control group.Results RBC-C 3b R in AMI is low significantly(p<0. 01), RBC-ICR increased significantly (p<0.01);the immunity disorder had changed into normal after the treatment with rt-PA.Conclusions Erythrocyte immunity adherence function is abnormal in the patients of AMI; Abnormal above can be changed by rt-PA thrombolytic therapy.