高频电波刀行电圈切除治疗宫颈病变的效果观察

Study of loop electrosurgical excision procedure in the treatment of cervical diseases

目的 探讨高频电波刀行电圈切除 (LEEP)治疗宫颈病变的临床效果及应用价值。方法 对2 32例 (其中 12 5例为CIN)LEEP治疗的宫颈病变患者进行回顾性分析。所有病例均行阴道镜下多点活检和LEEP术后病理诊断 ,在炎症和赘生物病变外缘 3mm进出电极 ,对于CIN和HPV感染患者 ,电极在病变边缘外 5mm进出。结果 LEEP治疗的宫颈病变治愈率为 96 98% ,CIN残留率和复发率低 ,分别为 2 4 0 %( 3/12 5 )和 1 6 0 % ( 2 /12 5 )。阴道镜下多点活检和LEEP术标本的病理诊断比较 ,差异有显著意义 (P <0 0 5 )。结论 LEEP对炎症、损伤、癌前病变、HPV感染等宫颈病变是一种非常理想的诊断。

Objective To study loop electrosurgical excision procedure(LEEP) in the treatment of cervical lesions.Methods 232 patients with cervical lesions underwent LEEP were studied.All the patients were treated by excision of 3mm or 5mm outside from the outskirts of the cervical lesions following colposcopy and biopsy.Results The overall cure rate in this study was 96.98% after first LEEP done.The residual CIN was identified in 3(2.40%) patients.The recurrence CIN occurred in 2(1.60%) patients.There was difference between biopsies directed by colposcope and LEEP specimens(P<0.05).Conclusion LEEP is a good method to diagnosis and treatment cervical lesions,especially in the treatment of CIN.The status of resection margin should be concerned.Margin involvement of specimen is the risk factor for residual and recurrence of CIN.