难治性甲状腺功能亢进的动脉栓塞治疗

Arterial embolization in the treatment of primary hyperthyroidism

目的 探讨难治性甲状腺功能亢进 (甲亢 )的有效治疗方法。方法 筛选难治性甲亢 7例 ,用微导管超选至甲状腺上、下动脉 ,采用聚乙烯醇颗粒为栓塞剂对靶动脉进行栓塞 ,治疗后随访 3个月至 1年 ,观察疗效和并发症。结果 7例患者症状和体征明显改善或消失 ,甲状腺功能指标明显降低或恢复正常 ,无一例严重并发症发生。

Objective To probe into an effective new therapy for primary hyperthyroidism.Hyperthyroidism is a major problem in the endocrinjum which is treated with internal medicine,thyroidectomy and radioiodine traditionally.The above three therapics have some disadvantages individually.Arterial embolization is a new method for primary hyperthyroidism which has a sufficient pathological basis.Methods We chose 7 cases of primary hyperthyroidism.We selected the superior and inferior arteries of thyroid after angiography,and then we used polyvinyl alcohol as embolic agents to embolize the target arteries.We observed the efficiency and complications.Results The hypermetabolic symptoms disappeared one to two weeks after embolization and the levels of T 3,T 4 decreased to normal.There was no severe complications.Conclusion Arterial embolization is an effective therapy for primary hyperthyroid,especially for those patients who can not be treated by traditional therapies.