低浓度汞接触对机体行为功能的影响——计算机化神经行为评价系统的应用

PSYCHOLOGICAL EFFECTS OF LOW EXPOSURE TO MERCURY VAPOR—APPLICATION OF A COMPUTER-ADMINISTERED NEUROBEHAVIORAL EVALUATION SYSTEM

应用中文版计算机化神经行为评价系统(NES-C)和情感状态问卷(POMS),对88名接触汞蒸气工人和70名对照人群.进行神经行为功能测试。结果提示,汞接触组工人的消极性情感状态得分增高,心算、数字检索、注意力调转、视复杂反应时及指叩等行为功能受到明显影响(P<0.05～0.01)。研究表明,NES-C适用于接触职业性有害因素,特别是神经性毒物的健康监护。

A computer-administered neurobehavioral evaluation 'system in Chinese language version (NES-C) and a mood inventory of the Profile of Mood States (POMS) were applied to assess the psychological effects of low level exposure to mercury vapor in a group of 88 workers (19 males and 69 females, with mean age 34.2 years) exposed to mercury vapor (average duration of exposure 10.4 years) . The well-matched group of 70 non-exposed workers was treated as controls.The intensity of current mercury vapor was relatively mild as reflected by the average level of mercury at air of workplace (0.033mg/m3) and in urine (0.025mg/L) . The results indicated that the profile of mood states was posed moving to the negative side in Hg-exposed group and most of the NES-C performances, in particular, the mental arithmetic, two digit search, switching attention, visual choice reaction time and finger tapping were also significantly affected compared with those obtained from controls (P<0.05-0.01) . The present study as well as the previous study on the validation of the system suggest that the NES-C we developed is valid for the neurotoxicity screening among working population exposed to neurotoxic agents.