摘要
原子力显微镜 (AFM)是近十几年来表面成像技术中最重要的进展之一。它具有非常高的分辨率。本文将阐述原子力显微镜的工作原理 ,分析原子力显微镜在生物医学中的应用现状 ,包括生物医学样品的表面形貌观测 ,在液体中的观测 ,生物分子之间力谱曲线的观测 ,以及生物医学样品制备技术等。
AFM is one of the most important development in the surface image techniques in the recent ten years It showed high resolution to the level of nanometer The basic principle of AFM and its application in biomedical area were reviewed in the paper, including the morphologic dtudies of cells and large moleculars,as well as monitoring biomolecular interactions The preparation of biomedical specimen were also discussed
出处
《现代仪器》
2004年第4期1-5,共5页
Modern Instruments
基金
"原子力显微镜分析技术方法体系的建立与应用"获 2 0 0 2年度国家科技部条财司分析测试新技术方法研究项目资助。科〔2 0 0 2 0 6〕
