天红口服液治疗急性脑梗死风痰瘀阻证临床研究

Clinical Study of Tianhong Oral Liquid on the Wind-phlegm Syndrome and Stasis in Acute Cerebral Infarction

目的 研究天红口服液治疗急性脑梗死风痰瘀阻证的临床疗效并探讨其可能的作用机制。方法 对入选病例 60例急性脑梗死风痰瘀阻证病人进行随机对照研究 ,治疗组用天红口服液结合西药治疗 ,对照组采用单纯西药治疗 ,治疗前及疗程结束后均进行神经功能缺损评分及中医证候评分 ,疗程结束后进行脑血流量(CBF)测定。结果 治疗组与对照组相比 ,神经功能缺损评分和中医证候评分明显改善(P <0 .0 1) ,CBF增加 (P <0 .0 1)。结论 天红口服液能改善急性脑梗死风痰瘀阻证病人神经功能缺损 ,改善其中医临床证候 ,可作为治疗急性脑梗死风痰瘀阻证的有效药物。

Objective To observe the clinical effect of Tianhong Oral Liquid on the wind-phlegm syndrome and stasis in acute cerebral infarction and explore its mechanism.Methods 60 patients differentiated as stagnation of wind-phlegm and stasis with ACI were randomly divided into two groups: the treatment group with Tianhong Oral liquid and western medicine and the control group treated only with western medicine. Before and after treatment, we evaluated the function of neural system and TCM (Traditional Chinese Medicine) symptoms respectively in two groups and gave scores. After treatment CBF(cerebral blood flow) was measured.Results Compared with the control group, in the treatment group , the scores of function of neural system and the evaluation of TCM symptoms show obvious improvement and CBF is higher. The differences between two groups were significant (P<0.01).Conclusion Tianhong oral liquid can improve neuronal cell function on the syndrome of stagnation of wind-phlegm and stasis in acute cerebral infarction, improve patients' clinical symptoms of TCM and be recommended as an effective medicine.