基因的多效性与中医理论的气化作用考辨

A Primary Studies on the Pleiotropism of Genes and the Effecting,Qihua of TCM Theory

从已有的报道中总结出 :任一个体的基因组里 ,疾病基因谱的表达总受体质、年龄 (即基因相互作用 )与环境条件 (含病源生物 )而异 ,并影响着某些基因的多效性方向 ,从而相同的基因谱可控制不同的表型 ,而这些多效性基因效应定向的过程与中医所谓的气化一词的含义相似。任一病理的气化基因组合 ,虽然是变化的 ,但在不同的病理阶段总可以表现出寒热、虚实、表里、阴阳等 4类八纲之中的 1项以上的属性证候 ;同时分别均有其对应的气化基因组合控制它们的表征。

Through a lot of data analysis,there are conclusions as follows: For expression of a profile controlling disease are vary with the soma-constitution,age for inference in gene interaction and environment as climate,bacteria and virus and inference to the vector of gene pleriotropism,therefore same gene can control different phenotype,symptom or disease at same time.And so on the process to form a functional profile in certain vector is similar with the conception of the Qihua as effecting theory in TCM.Although any Qihua,effecting pathological profile are vary at various stage of a disease or pathology but there are a symptom complex in general term exhibition on one or more of the Eight Pattern as Cold or Heat,Deficiency or Excess,Interior or Exterior and Yin or Yang and there are an effecting profile to control the phenotype responded respectively.