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动态检测乳腺癌血浆血管内皮生长因子的临床意义初探 被引量:2

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摘要 目的 探讨乳腺癌患者血浆血管内皮生长因子 (P VEGF)手术前后及发生转移时可能的变化情况及其临床意义。方法 采用酶联免疫吸附试验 (ELISA)检测不同类型的乳腺癌 (39例乳腺浸润性导管癌、2 8例乳腺浸润性小叶癌、9例复发转移性乳癌 )患者P VEGF水平 ,并进行比较分析。结果 术前乳腺浸润性导管癌P VEGF水平明显高于浸润性小叶癌 (P =0 .0 0 0 ) ,与术后 7dP VEGF水平比较无差异(P >0 .0 5 ) ,术后 30dP VEGF水平明显低于术前和术后 7d的水平 (P <0 .0 5 ) ;浸润性小叶癌手术前及手术后 7、30dP VEGF水平比较无显著差异 (P均 >0 .0 5 )。复发转移性乳腺癌P VEGF水平明显高于前二者水平 (P均 <0 .0 5 )。结论 P VEGF在浸润性导管癌中的水平高于浸润性小叶癌中的水平 ,复发转移性乳腺癌的P VEGF水平更高 ,可以作为乳腺癌。
出处 《中国综合临床》 北大核心 2004年第9期821-823,共3页 Clinical Medicine of China
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同被引文献9

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