1Tian H, Hammer RE, Matsumoto AM, et al. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev, 1998,12(21 ): 3320-3324.
2Talks KL, Turley H, Gatter KC, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol,2000, 157(2) :411-421
3Gu YZ, Moran SM, Hogenesch JB, et al. Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha. Gene Expr, 1998, 7(3):205-213.
4Zhong H, De Marzo AM, Laughner E, et al. Overexpression of hypoxiainducible factor lalpha in common human cancers and their metastases.Cancer Res, 1999, 59(22) :5830-5835
5Na X, Wu G, Ryan CK, et al. Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas. J Urol, 2003, 170(2 Pt 1):588-592.
6Liu MY, Pcellinger L, Walker CL. Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene. Cancer Res, 2003,63 (10): 2675-2680.
7Mizukami Y, Li J, Zhang X, et al. Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer. Cancer Res, 2004, 64(5): 1765-1772.
8Bos R, van der Groep P, Greijer AE, et al. Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer, 2003,97(6): 1573-1581.
9Buchler P, Rebar HA, Buchler M, et al. Hypoxia-inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer. Pancreas, 2003,26(1) :56-64.
10Sivridis E, Giatromanolaki A, Gatter KC, et al. Association of hypoxiainducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. Cancer, 2002,95(5): 1055-1063.