摘要
Five natriuretic peptides (NP) have been identified: A-type, B-type, C-type, D-type and V-type. All of them have ringed-structures. The actions of the natriuretic peptides are modulated through their cognate receptors, which are named as NPR-A,NPR-B and NPR-C. The receptors are involved in the cGMP-dependent signaling cascades,which take part in many different physiological regulation, such as diureses,vasodilatation, depressing blood pressure, improving immunity, promoting development of bone, regulating nerve system and so on. At present, ANP and BNP have become a marker in diagnostic some cardiovascular diseases.
Five natriuretic peptides (NP) have been identified: A-type, B-type, C-type, D-type and V-type. All of them have ringed-structures. The actions of the natriuretic peptides are modulated through their cognate receptors, which are named as NPR-A,NPR-B and NPR-C. The receptors are involved in the cGMP-dependent signaling cascades,which take part in many different physiological regulation, such as diureses,vasodilatation, depressing blood pressure, improving immunity, promoting development of bone, regulating nerve system and so on. At present, ANP and BNP have become a marker in diagnostic some cardiovascular diseases.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2004年第8期1517-1521,共5页
Chinese Journal of Pathophysiology
基金
国家重点基础研究发展规划项目 (973) (No .G2 0 0 0 0 5 6 90 4 )
国家自然科学基金资助项目 (No.30 0 70 311)
关键词
利钠肽
心血管疾病
免疫力
Natriuretic peptide
Cardiovascular diseases
Immunity
