深圳企事业职员5 571例体质量指数与脂肪性肝病的流行病学调查

Epidemiological investigation on body mass index and fatty hepatopathy in 5 571 office workers in Shenzhen enterprises

目的运用流行病学调查手段,探讨不同性别、年龄人群体质量指数(bodymassindex,BMI)与脂肪性肝病的关系,以期为早期干预及改善脂肪性肝病预后提供依据。方法对2003年上半年深圳地区企事业单位的5571例健康体检者按BMI分为正常组、超重组、肥胖组进行腹部B超、肝功能的检查,对其结果进行统计分析。结果①肥胖症总发生率32.01%,其中男性42.45%,女性16.53%。②男女各年龄组脂肪肝的检出均随着BMI的增加而显著增加(χ2=32.953～380.177,P<0.01)。③男性组总脂肪肝合并谷丙转氨酶异常的检出率随着BMI的增加而增加(χ2=7.635,P<0.05),但各年龄组间差异无显著性意义(P>0.05)。结论肥胖是导致脂肪性肝病的主要因素。

AIM:To explore the relationship between the body mass index(BMI) and fatty hepatopathy of different ages and genders,and to provide evidence for early intervention and amelioration of fatty hepatopathy prognosis by the method of epidemiological investigation.METHODS:After health exemination,in the first half year of 2003,a total of 5 571 office workers in the enterprises in Shenzhen were divided into normal group,overweight group and obesity group according to their BMI,given B mode ultrasonography imaging on abdomen and liver function,and then the results were analyzed statistically.RESULTS:①The total incidence rate of adiposity was 32.01%(42.45%for male and 16.53%for female).②The occurrence of fatty liver in the population at various age stages was significantly increased as the increase of BMI(χ2=32.935-380.177,P< 0.01).③The incidence rate of abnormality of total fatty liver combining with transaminase was increased as the increase of BMI(χ2=7.635,P< 0.05),while no significant difference was observed among various age groups(P >0.05).CONCLUSION:Obesity is a main factor that results in fatty hepatopathy.