肺癌肉瘤的临床观察

The clinical observation of pulmonary carcinosarcoma

目的 探讨肺癌肉瘤的临床病理特点、组织来源、诊断及治疗。方法 收集近 8年来收治的 8例肺癌肉瘤患者的临床资料 ,结合文献进行回顾性分析。结果 8例肺癌肉瘤光镜下表现为既含癌又含肉瘤两种成分的复杂性肿瘤 ,临床上与原发性支气管肺癌无特征的区别 ,只有通过组织病理结合免疫组化标记才能明确肺癌肉瘤的各种成分的表达。结论 肺癌肉瘤与原发性支气管肺癌在临床表现以及各种辅助检查上易混淆 ,且预后差。首选治疗为手术切除。

Objective To evaluate the clinical and pathological characteristics and investigate the origin of pulmonary carcinoma and improve the diagnosis and treatment of pulmonary carcinosarcoma. Methods Retrospective study was conducted in a total of 8 cases of lung carcinosarcoma hospitalized in late eight years. Results Lung carcinosarcoma is rare, microscopically the tumors were composed of both carcinomatous and sarcomatous elements. It was not distinguishable from brondrogenic carciniose preoperatively and was found to be of epithelial and mesenchymal elements with different characteristic features under the microscopy or immunohistochemistry methods. Conclusion Lung carcinosarcoma is easily misdiagnosized as brondrogenic carcinose by clinical features and examinations and its prognosis is poor.Surgical intervention is the first choice.