阿尔茨海默病抗Aβ治疗的研究进展
Treatment inhibits beta-amyloid accumulation in Alzheimer's disease
出处
《西北国防医学杂志》
CAS
2004年第4期290-291,共2页
Medical Journal of National Defending Forces in Northwest China
参考文献11
-
1Golde TE.Alzheimer disease therapy: Can the amyloid cascade be halted [J]?J Clin Invest,2003,111(1):11-18.
-
2Wolozin B, Kellman W, Ruosseau P, et al.Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors[J].Arch Neurol, 2000, 57:1439-1443.
-
3Cherny RA, Atwood CS, Xilinas ME, et al.Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice[J].Neuron, 2001, 30: 665-676.
-
4Selkoe DJ.The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics[J].Science, 2002, 297:353-356.
-
5Dovey H, Varghese J, Anderson JP.Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in the brain[J].J Neurochem, 2000, 76:1-10.
-
6Luo Y, Bolon B, Kahn S, et al.Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation[J].Nat Neurosci, 2001, 4:231-232.
-
7Schenk D, Barbour R, Dunn W, et al.Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse[J].Nature,1999, 400:173-177.
-
8Smith, A.Putting the brakes on cognitive decline[J].Nat reviews, 2003, 2:507.
-
9Lim GP, Yang F, Chu T, et al.Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease[J].J Neurosci, 2000, 20:5709-5714.
-
10Refolo LM, Pappolla MA, LaFrancois J, et al.A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model[J].Neurobiol Dis, 2001, 8:890-899.
-
1郁向静,何俊民.β淀粉样蛋白在阿尔茨海默病中的病因学作用[J].广州医药,2007,38(2):7-10. 被引量:5
-
2严蓉,李战,杨修庚,于锋.依达拉奉注射液治疗急性缺血型脑梗死有效性的临床评价[J].中国临床药理学与治疗学,2011,16(2):190-195. 被引量:6
-
3刘伟(摘译).β淀粉样蛋白沉积大脑记忆力并不受损——科学家发现预防阿尔茨海默氏症新途径[J].基础医学与临床,2006,26(6):620-620.
-
4张辉,郝晓艳,周丽.浅谈帕金森病与骨质疏松[J].中国民康医学,2015,27(24):76-77.
-
5秦川.老年痴呆动物模型研究进展[J].中国药理通讯,2007,24(2):58-58. 被引量:1
-
6朱丹,纪超,左萍萍.阿尔茨海默病的相关免疫机制及治疗研究进展[J].中华脑科疾病与康复杂志(电子版),2014,4(3):34-37. 被引量:2
-
7汤兆君.老年性痴呆的脑功能障碍及治疗方向[J].现代中西医结合杂志,2008,17(13):2105-2106.
-
8张笋,姚泰.雌激素对淀粉样β蛋白代谢的调节和毒性缓解[J].生理科学进展,2003,34(3):197-201. 被引量:1
-
9刘中海,林玲.褪黑激素、多巴胺、谷氨酸、γ-氨基丁酸与帕金森病的研究进展[J].中国社区医师(医学专业),2012,14(10):18-18. 被引量:3
-
10王辉,李林.Alzheimer病中枢和外周的炎症改变[J].中国老年学杂志,2003,23(10):636-639.