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功能型二元酸的制备 被引量：2

Synthesis of Novel Functional Diacids
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摘要 以四氢呋喃作溶剂,用具有生物相容性的己二酸酐分别与甘氨酸、L 丙氨酸以及邻羟基苯甲酸反应,一步合成了3种功能型二元酸:5 羧甲基氨基甲酰戊酸、5 (1 羧乙基)氨基甲酰戊酸、己二酸单(2 羧苯酚)酯.对反应中间体和目标化合物进行红外(IR)光谱、核磁共振氢谱(1HNMR)表征,证实了它们的结构和组成.同时探讨了反应溶剂及反应时间对产物合成的影响. 5-(Carboxymethyl-carbamoyl)-pentanoic acid, 5-(1\|carboxy-ethylcarbamoyl)-pentanoic acid and hexanedioic acid mono-(2-carboxy-phenyl) ester were synthesized by reacting adipic anhydride with glycine, L\|alanine and o-hydroxy benzoic acid respectively, using anhydrous THF as solvent. The intermediate and objective products were identified by spectrum of IR,^(1)H NMR. The influence of solvent and reaction time had been studied.
作者 张志琴 苏新梅 白毓 赵保敏 李蔚 曲凡歧
机构地区 武汉大学化学与分子科学学院 新乡师范专科学校化学系
出处 《武汉大学学报（理学版）》 CAS CSCD 北大核心 2004年第4期463-466,共4页 Journal of Wuhan University:Natural Science Edition
基金 国家重点基础研究发展规划项目资助(G1999064703)
关键词 5-羧甲基氨基甲酰戊酸 5-(1-羧乙基)氨基甲酰戊酸 己二酸单(2-羧苯酚)酯 合成 单体 5-(carboxymethyl-carbamoyl)-pentanoic acid 5-(1-carboxy-ethylcarbamoyl)-pentanoic acid hexanedioic acid mono-(2-carboxy-phenyl) ester synthesis monomer
分类号 O631 [理学—高分子化学]
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参考文献16

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二级参考文献25

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共引文献11

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武汉大学学报（理学版）
2004年 第4期

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