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氨基胍对实验性糖尿病大鼠心肌的保护作用 被引量:1

Protective effect of aminoguanidine on diabetes-induced myocardial injury
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出处 《中国药理学通报》 CAS CSCD 北大核心 2004年第8期956-956,共1页 Chinese Pharmacological Bulletin
关键词 氨基胍 糖尿病大鼠 心肌病 aminoguanidine diabetic rat cardiomyopathy
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参考文献4

  • 1张芳林,李果.糖尿病性心肌病发病机理的研究进展[J].国外医学(内分泌学分册),2002,22(4):245-247. 被引量:24
  • 2Ren J, Gintant GA, Miller RE et al. High extracellular glucose impairs cardiac E-C coupling in a glycosylation-dependent manner[J]. Am J Physiol, 1997,273(Pt 2):2876-83.
  • 3Namba T, Tsutsui H, Tagawa H et al. Regulation of fibrillar collagen gene expression and protein accum lation in volume-overloaded cardiac hypertrophy[J]. Circulation,1997,95(10):2448-54.
  • 4Hammes HP, Martin S, Federlin K et al. Aminoguanidine treatment inhibits the development of exepermental diabitic retinopathy[J].Proc Natl Acad Sei USA, 1991,88(24):11555-8.

二级参考文献14

  • 1Laakso M. Hyperglycaemia and cardiovascular disease in type 2 diabetes [J]. Diabetes, 1999,48:937-942.
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共引文献23

同被引文献5

  • 1Fang Z Y,Prins J B,Marwick T H.Diabetic cardiomyopathy:evidence,mechanisms,and therapeutic implcations[J].Endocr Rev,2004,25(4):543-67.
  • 2Li C Y,Cao L S,Zeng Q T,et al.Taurine may prevent diabetiv rats from developing cardiomyopathy also by downregulating angiotensinⅡtype2 receptor expression[J].Cardiovasc Drugs Ther,2005,19(2):105-12.
  • 3Yue T L,Bao W,Gu J L,et al.Rosiglitazone treatment in Zucker diabetic Fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion-induced myocardial injury[J].Diabetes,2005,54(2):554-62.
  • 4Ghosh S,Qi D,An D,et al.Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA[J].Am J Physiol Heart Circ Physiol,2004,287(6):2518-27.
  • 5Malhotra A,Begley R,Kang B P,et al.PKC-{epsilon}-dependent survival signals in diabetic hearts[J].Am J Physiol Heart Circ Physiol,2005,289(4):H1343-50.

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