颅骨骨纤维异样增殖症磁共振表现

Fibrous Dysplsia of Cranial Bone:MRI findings

目的 研究颅骨骨纤维异样增殖症的MRI表现。方法回顾性分析22例颅骨骨纤维异样增殖症的MRI表现。其中男12例,女10例,年龄2～74岁,平均22.8岁。10例MRI平扫和增强扫描,12例单纯MR平扫。结果22例患者,临床主表现为头局部膨胀、突眼及复视、头痛。MR平扫,T1WI上表现低信号者14例,等信号8例。T2WI上表现多种多样,低信号12例,混杂信号8例,高信号2例。增强扫描,颅底骨病变多明显均匀强化,颅盖骨多不均匀斑片样强化。结论颅盖骨骨纤维异样增殖症的MRI表现有一定特异性,而颅底病变表现常类似肿瘤改变,应提高对该病MRI表现的认识,以降低误诊率。

Objective To study MRI findings of fibrous dysplasia involvement of cranial bones.Methods MRI finds of 22 patients with fibrous dysplasia involvement of cranial bones were reviewedretrospectively. All cases were proved by operation and clinic.12 male and 10 female,ranging in age from2～74 years old,mean age 22.8 years.10 cases were examined with both precontrast and postcontrast of MRscanning,12 cases were examined only with precontrast MR sanning. Results The main clinical manifes-tation of 22 patients are skull proptosis and headache and asymptomatic. On T1WI,14 cases appearedhypointensity and 8 cases isointensity. The signal intensity of fibrous dysplasia on T2WI was oftenvariable, ranging from low signal to high signal. The fibrous dysplasia of the base of the skull weremarkedly enhanced by injection of constrast medium in most cases. Otherwise heterogeneous enhancementwere noticed in other regions. Conclusion MRI findings of cranial fibrous dysplasia reveal somedistinctive features of the disease. An awareness of this potential diagnosis can help to reduce thepossibility of misdiagnosing of fibrous dysplasia.