双侧乳腺癌的临床分析(附9例报告)

Bilateral breast cancer :a clinical study of 9 cases

目的探讨双侧乳腺癌的特点及预后因素。方法对我科从1998年1月～2002年12月收冶的9例双侧乳腺癌病人进行分析。结果 本组病人平均年龄46.8岁。同时性双侧乳腺癌3例,异时性双侧乳腺癌6例。第一原发癌:Ⅱ期4例,Ⅲ期5例。第二原发癌:Ⅰ期3例,Ⅱ期5例,Ⅲ期1例。第一原发癌:ER阳性5例,PR阳性5例。第二原发癌:ER阳性5例,PR阳性4例。结论对于乳腺癌术后病人,应重对侧乳腺的检查,特别是在1年以内。双侧乳腺癌的治疗方法和单侧乳腺癌一样,两者的生存率无差别。双侧乳腺癌一般第二原发癌比第一原发癌早期,两者发生的时间间隔越长,治疗效果越好。

Objective To study the characteristic and the prognostic factors bilateral breastcancer.Methods The data of 9 cases treated from January 1998 to December 2002 were retrospectivelyanalyzed.Results The medianage was 46.8 years.3 cases were the synchronous bi lateral breast cancer ,6cases were the metachronous bi lateral breast cancer.The first breast carcinoma:4 cases were stage Ⅱ,5 cases were stage Ⅲ.The second breast carcinoma:3 case were stageⅠ,5 cases were stage Ⅱ, 1 case wasstageⅢ.The first breast carcinoma:5 cases were estrogen-receptor positive,and 5 cases were progester-one-receptor posetive.The second breast carcinoma:5 cases were estrogen-receptor positive.The secondbreast carcinoma; 5 cases were estrogen-receptor positive, and 4 cases were progesterone-receptorpositive.Conclusion The contralateral breast must be checked regularly in the postoperative patients,specially in l year.The therapy of bilateral and unilateral breast cancer is just the same.The survivalrate is similar for the bi lateral and unilateral breast cancer patients.Time interval between the firstand second breast carcinoma is longer , and the survival rate is better.