血淋巴结内高内皮微静脉和淋巴迷路的形态学研究

Morphologic study of the high endothelial venules and lymphatic labyrinths in the hemolymph node

目的 观察血淋巴结内高内皮微静脉和淋巴迷路的形态 ,探讨血淋巴结内淋巴细胞归巢的径路。方法 采用光镜、透射电镜和扫描电镜的方法观察大鼠血淋巴结的构造。结果 血淋巴结内高内皮微静脉分布广泛 ,内皮细胞高大且凸向管腔 ,细胞器丰富 ,可见淋巴细胞附着或穿越内皮细胞内和细胞连接间隙。副皮质区内可见管状或袋状的充满小淋巴细胞的淋巴迷路结构。

Objective To investigate the pathways of the lymphocytes homing in the hemolymph node,through the morphologic study of the high endothelial venules(HEVs) and lymphatic labyrinths in the hemolymph node.Methods We observed the structure of the rat hemolymph node by light microscopy,transmission electron microscopy and scanning electron microscopy.Results There were plenty of the HEVs in the hemolymph nodes.The endothelial cells were thick and process to the lumen.The organelles in the high endothelial cells were plentiful.The lymphocytes were found to adhere or penetrate the endothelial cells and the junction septum of the endothelial cells.In the paracortex of the hemolymph nodes,the tubular or pocket lymphatic labyrinths which were densely filled with small lymphocytes were found.Conclusion The hemolymph nodes are one of the important situations of the lymphocytes homing.