69例声门癌的临床病理学分析

Clinic histopathology of 69 cases of glottic carcinoma

目的 探讨声门癌浸润特点及浸润途径 ,为临床手术治疗声门癌提供理论依据。方法 应用火棉胶包埋、组织大块连续切片的方法 ,对 6 9例声门癌进行临床病理学研究。结果 6 9例患者中 ,声带活动良好 34例 ,声带活动受限 10例 ,声带固定 2 5例。声门癌的生长方式以丛生团块和丛生浸润为主 ,分别为 2 4例和 2 1例。T、P分期 :T1分期在声门癌发病比例较高 ,为 34例 ,P1期为 31例 ;鳞癌分级以高分化为主 ,Ⅰ、Ⅱ级分别为 2 8例和 32例。结论 声门癌多以黏膜及黏膜下浸润为主 ,肿瘤一旦侵及前联合可侵及对侧声带或侵犯甲状软骨 ,也可由前联合腱侵犯环甲膜而达喉外。声门癌生长方式以丛生团块和丛生浸润为主。组织分化程度以Ⅰ、Ⅱ级为主 。

Objective To study the infiltrative trait and channel of the glottic carcinoma,and to apply the theory to the surgery of the disease.Methods The tissues of the 69 patients were wrapped with collodion,and made large successive section for the study of histopathology.Results Among the 69 cases,the movement of the vocal cords:well (34),impaied (10),fixed (25).The main growth styles were plexiform mass (24),and plexiform infiltration (21).T,P phase:the rate of T 1 phase was higher,34 cases;while P 1 phase,31 cases.The grade of squamous carcinoma was mainly high differentiation,Ⅰ(28);Ⅱ(32).Conclusion The glottic carcinoma usually infiltrates mucosa and submucosa,once it invades the anterior commissure,the opposite cord and the thyroid cartilage will be invaded,or from anterior commissure via cricothyroid membrane to the outside of the larynx.Plexiform mass and plexiform infiltration are the main growth style.Ⅰ,Ⅱare the main grade,and it has no special connection with the growth style.