我院临床抗生素应用与细菌耐药性分析

Application of clinical antibiotics and analysis of bacterial drug resistance in our hospital

目的 对我院 1999年 7月 2 0 0 1年 7月抗菌药物的用药情况进行统计 ,了解我院感染病原菌的排序及细菌的耐药性情况。方法 对 1999年 2 0 0 1年抗生素的出库根据其出库数量、消耗金额进行统计 ,并对二年内临床送检标本进行细菌培养和药物敏感度实验进行分析。结果 统计结果显示青霉素类、头孢菌素类、喹诺酮类、氨基糖苷类临床用药最为广泛。通过对2 0 5 1例样本的实验分析 ,耐药菌株 917例为 4 4 .7% ,敏感菌株 1134例为 5 5 .3%。结论 通过各种措施选择正确的抗生素治疗方案 ,做到有指征的优先选用低耐药性药物 ,限用高耐药可能性药物 。

OBJECTIVE To lean the order of infected nosoplyte and the situation of bacterial drug resistance. METHOD The cost and the quantity of antibiotics in 1999～2001 were statistical analyzed, the clinical specimens were incubated and the drug susceptivity were analyzed.RESULTS Penicillins, cephalosporins, quinoloues and iminoglycoside were the widest use in clinical. There were 917(44.7%) drug-resistant strains and 1134(55.3%) drug-sensitive strains in 2051 strains.CONCLUSION To use antibacterial reasonably, the high drug-resistance possible drug should be limited.