^(13)C-UBT对儿童感染幽门螺杆菌的诊断价值

The Diagnostic Value of ^(13)C-UBC for Children's Hp Infections

目的 :探讨1 3 碳 -尿素呼气试验 (1 3 C -UBT)对儿童感染幽门螺旋杆菌的诊断价值。方法 :对 99例无症状儿童及 1 0 5例反复腹痛患儿分为两个组 ,各自再分为 (～ 4、～ 7、～ 1 0、～ 1 4 )四个年龄段作1 3 C -UBT。结果 :无症状儿童组Hp感染阳性率为 1 1 .1 % ,反复腹痛患儿组Hp感染阳性率为 2 5 .7% ,两组间有显著性差异 (P <0 .0 1 ) ;无症状儿童组四个年龄段Hp感染阳性率分别为 7%、9%、1 2 %、1 4 % ,且显示随着年龄的增长Hp感染阳性率递增 ,但无显著性差异 (P >0 .0 5 )。反复腹痛患儿组四个年龄段Hp感染阳性率分别为 2 2 %、2 7%、2 6 %、2 8% ,其与年龄无关。结论 :1 3 C -UBT是一种快速、简便、敏感性和特异性好、准确性高无创伤性的Hp诊断方法 ,有重要的临床诊断价值。

Objectives:To investigate the diagnosis of Helicobacter Pyloi(Hp) infection with the method of 13 C-urea breath test( 13 -UBT).Methods:99 normal children and 105 Patients of repeated stomachache were separated respectively in four groups according to their ages(～4,～7,～10,～14). 13 C-UBT were applied on two groups.Results:The Hp infection rate of the normal group was 11.1%,but it was 25.7% of the stomachache group.It was significantly different between two groups.The infection rates of different age groups of normal children were 7%,9%,12%,14%,ascending with the age growing;but there were no significant differences.For the stomachache cases,the Hp infection rates of 4 age groups were 22%,27%,26%,28% respectively without relationship with ages.Conclusion: 13 C-UBT is a repid,simple,acute,sensitive and distinctive method for diagnosis of Hp infection without injury and with significant valre for clinical diagnoses.