全髋关节置换术后预防深静脉血栓形成的研究

A study on prevention of deep vein thrombus in patients underwent total hip replacement

[目的 ]观察全髋关节置换术后使用感应性抗血栓泵 (SCD )、速碧林预防深静脉血栓 (DVT )形成的效果。 [方法 ]将 160例单侧人工全髋关节置换术病人随机分为 4组 ,即空白对照组、感应性抗血栓泵组、速碧林组、感应性抗血栓泵加速碧林组。术后第 1天开始使用 ,连续使用 7d。术后第 8天通过超声多普勒检查确诊有无DVT形成。[结果 ] 4组DVT的发生率分别为 3 7.5 %、15 .0 %、2 0 .0 %、5 .0 % ,空白对照组有 1例肺栓塞发生 ,经 χ2 检验 ,有统计学意义(P <0 .0 5 )。 [结论 ]全髋关节置换术后 ,单纯使用抗血栓泵或速碧林可以有效地降低DVT的发生率 ,综合使用两种方法效果更佳。

Objective: to observe on the effect of applying SCD irritability anti-thrombus pump and Nadroparin Calcium Injection to prevent deep vein thrombus (DVT) in patients underwent total hip replacement. Method: a total of 160 patients who would be undergoing unilateral artificial total hip replacement were divided into 4 groups randomly, that was blank control group, SCD group, Nadroparin Calcium Injection group and combination of SCD and Nadroparin Calcium Injection group. The countermeasures were started on the first day after operation for 7 days. All patients were checked via ultrasound Doppler to confirm if he had got deep vein thrombus on the eighth day after operation. Result: the incidences of DVT in each group patients were 37.5%, 15.0%, 20.0% and 5.0% respectively. Among them, a case of blank control group developed pulmonary embolism. There were significant differences between these groups (χ 2 test,P<0.05). Conclusion: it is effective to decrease the incidence of DVT for patients undergoing total hip replacement by using either SCD or Nadroparin Calcium Injection only. However the efficiency would be improved much better by combining SCD and Nadroparin Calcium Injection.