低钙透析液用于血液透析的临床观察

The clinical investigation of low-calcium dialysate in hemodialysis

目的 探讨低钙透析液用于血液透析的有效性及安全性。方法 采用稀释后浓度为 1.2 5mmol/L碳酸低钙透析液 ,常规透析治疗 2 4例高钙血症血液透析患者的规律。结果 观察高钙血症血液透析患者在应用碳酸低钙透析液 3个月和 6个月后 ,血钙、钙磷乘积、iPTH的指标变化及不良反应。结果发现血钙下降水平与低钙透析液使用前比较有明显差异 (P <0 .0 5 ) ;钙磷乘积也有显著性差异 (P <0 .0 5 ) ;血磷无显著性差异 (P >0 .0 5 ) ;iPTH无显著性差异 (P >0 .0 5 )。结论 高钙血症的血液透析患者在使用低钙透析液后 ,血钙下降明显、可有效降低钙磷乘积 ,可能有益于减轻血液透析患者骨外转移性钙化的发生。

Objective To investigate the clinical effect of low-calcium dialysate in the treatment of the hypercalcemia of hemodialysis patients. Methods Low-calcium dialysate (1.25mmol/L) was used in 24 hemodialysis patients of hypercalcemia. Results There were significant difference between low-calcium dialysate was used before and after three months and six months in blood calcium (P<0.05), and there were also significant difference in Ca×iP (P < 0.05). There were no singnificant difference in blood phosphorus (P>0.05) and in iPTH (P>0.05). Conclusion There were significant difference between low-calcium dialysate was used before and used after three months and six months in blood calcium with hypercalcemia. It is effect to reduced calcium transfer from body's bone to other body's organs.