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子宫内膜异位症患者腹腔液细胞因子测定及临床意义

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摘要 目的 探讨子宫内膜异位症患者腹腔液细胞因子测定及临床意义。方法 将 6 4例子宫内膜异位症患者作为研究对象 ,2 5例正常妇女为对照组 ,开腹手术中取腹腔液 ,采用酶联免疫吸附法测定IL 6 ,IL 8及TNF α。结果与对照组相比 ,子宫内膜异位症两组患者腹腔液中IL 6、IL 8、TNF α水平均明显高于对照组 (P <0 .0 5 )。在子宫内膜异位症患者中 ,重度组患者腹腔液中IL 6、IL 8、TNF α水平均明显高于轻度组 (P <0 .0 5 )。结论 子宫内膜异位症患者腹腔液中免疫功能紊乱 ,细胞因子IL 6、IL 8、TNF α产生过量 ,细胞因子的量随疾病分期的增加而增高 ,可能共同参与内异症的发病过程。
出处 《江西医学院学报》 2004年第4期70-71,共2页 Acta Academiae Medicinae Jiangxi
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