结节性硬化症的颅脑及肾脏CT表现

CT manifestations of brain and kidney in tuberous sclerosis

目的:探讨结节性硬化症的颅脑及肾脏CT表现,以提高对本病的诊断水平。方法:收集经临床及CT诊断的结节性硬化症35例,分析其颅脑及肾脏CT表现。结果:本组35例患者均有颅脑异常CT表现,其中室管膜下结节35例、皮层或/及皮层下结节16例、室管膜下巨细胞星形细胞瘤2例、脑白质内小片状低密度区5例、梗阻性脑积水4例;22例有肾脏异常CT表现,其中血管肌脂瘤18例、多发囊肿4例、动脉瘤2例。结论:结节性硬化症的颅脑及肾脏CT表现具有特征性,CT可作为检查结节性硬化症的首选方法。

Objective: To discuss the CT manifestations of brain and kidney in tuberous sclerosis and to improve the level of CT diagnosis. Methods: CT presentations of brain and kidney were analyzed in 35 cases of tuberous sclerosis. Results: The CT manifestations of brain were abnormal in all the 35 cases, among which there were 35 cases with subependymal nodules, 16 with cortical/subcortical tubers, 2 with subependymal giant cell astrocytoma, 5 with low density in white matter, and 4 with obstructive hydrocephalus. Of 22 cases with renal abnormality, 18 were demonstrated with angiomyolipoma, 4 with multiple cysts, and 2 with aneurysm. Conclusion: The CT manifestations of brain and kidney in tuberous sclerosis are characteristic, and the main manifestations are subependymal nodule and renal angiomyolipoma. CT should be the modality of choice for the diagnosis of tuberous sclerosis.