小儿药物性血尿32例临床分析

<title>inical Analysis of 32 Children with Medicinal Hematuria

目的探讨药物性血尿的常见原因及相关因素。方法 对32例药物性血尿患儿的临床资料进行回顾性分析总结。结果 在引起药物性血尿中,解热镇痛药15例(46.9％),先锋霉素7例(21.9％),氨基糖甙类抗生素5例(15.6％),另外磺胺药2例,氟哌酸1例,中药抗病毒冲剂2例也可引起血尿。药物性血尿的发生既可能与药物剂量有关(剂量依赖性),也可能与剂量无关(非剂量依赖性)。结论 引起药物性血尿的常见原因与不合理用药有关,临床医生应注意药物性血尿发生的危险因素。

<abstract>jective To learn the reason and associated factors of medicinal hematuria in children Methods The clinical data of 32 children with medicinal hematuria were analysed retrospectively. Results The heat-expelling and pain-relieving drugs were major causes that induced children medicinal hematuria(46.9%). Cephalosporins were the secondary(21. 9%). Aminoglucosides antibiotics were the third (15.6%). In addition, 3 of whom are induced hematuria by sulfonamides, norfloxacin, the Chinese medicine of Kang-bing-du Chong-ji, respectively. Some of medicinal hematuria occurrences were associated with the drug doses, but Some of medicinal hematuria have nothing to do with the doses. Conclusion The happening of medicinal hematuria has relation with the rational use of medicine, so pediatrician must realize any risk factors of medicinal hematuria occurrences.