宫颈上皮内瘤样病变与人乳头状瘤病毒感染(附331例病例分析)

<title>rvical Intraepitheial Neoplasia and HPV Infection:Report of 331 Cases

通过对331例宫颈疾病患者阴道镜下活检病理诊断结果的分析,发现在宫颈上皮内瘤样病变(CIN)中,CIN合并人乳头状瘤病毒(HPV)感染率为62.58%,宫颈炎合并HPV感染率为28.57%,两者比较有明显的差异.19～29岁年龄段的CIN患者合并HPV感染率较30～69岁年龄段明显增高.结果表明宫颈HPV感染促进了宫颈上皮内瘤样病变(CIN)的发生.年轻患者宫颈HPV感染率的增高,是宫颈癌患者年轻化的原因.因此,大力开展HPV感染检测,及早发现宫颈上皮内瘤样病变(CIN)并进行干预治疗是降低宫颈癌发病率的有效手段.

<abstract> investigate 331 patients with cervical intraepithelial neoplasia (CIN) by colposcopical and pathological observation. We found that the infection rate of CIN combination with human papillomavirus infection (HPV) was 62.58%, and the infection rate of cervical inflammation combination with HPV was 28. 57%. There was significant difference between two groups. The infection rate of CIN combination with HPV in 19-29 years of age was significant higher than in 30-69 years of age. The results shown that HPV infection can promote formation of CIN. Patients with cervical cancer became younger because of HPV infection. To detect HPV infection and treat early CIN might reduce the incidence of cervical cancer.