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复合用药与单纯用药对控制性降压效果的临床探讨 被引量:7

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摘要 目的探讨用硝酸甘油与硝酸甘油+艾司洛尔对内窥镜鼻窦手术患者行控制性降压的效果比较.方法38例择期内窥镜鼻窦手术患者,常规在静吸复合全麻下行内窥镜鼻窦手术.麻醉手术期控制降压以期减少术中出血的危险.降压药物分为硝酸甘油(Ⅰ组)及硝酸甘油+艾司洛尔(Ⅱ组).术中控制降压,将平均动脉压(MAP)降至并维持在60~65mmHg,监测降压期间MAP和HR的变化.结果Ⅰ组降压后HR明显增快,超过110次/min(P<0.05),停止降压后10min仍高于降压前值(P<0.05).Ⅱ组合并使用艾司洛尔50ug/kg/min,可减慢心率及减少硝酸甘油的用量30%(P<0.05).结论内窥镜鼻窦手术病人单纯使用硝酸甘油控制性降压,效果较差,反射性心率加快,联合使用硝酸甘油-艾司洛尔降压效果具有更优越的效果.
出处 《国际医药卫生导报》 2004年第16期141-142,共2页 International Medicine and Health Guidance News
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