杏贝颗粒中苦杏仁等药材提取工艺的正交实验研究

Orthogonal Study on Extraction Technique for Extracting Semen Pruni Armeniacae and Other Medicinal Materials from Xingbei Granule

目的 确定杏贝颗粒处方中苦杏仁等药材的最佳提取工艺条件。方法 以苦杏仁苷提取率和得膏率为指标 ,来考查药材前处理、加水量和煎煮时间对苦杏仁苷提取效果的影响。结果 最佳提取条件为 :苦杏仁沸下 ,加 (10 +8)倍水 ,煎煮 (2 +2 )h。结论 该最佳工艺是稳定可行的 ,可用于工业化生产。

OBJECTIVE To establish the optimal extraction technique for extracting Semen Pruni Armeniacae and other medicinal materials from Xingbei Granule. METHOD Observation was made on the effect of pre-treatment, water amount and decoction time on the extraction result, with the extraction rate of amygdaloside as the index.RESULT The best extraction conditions: Semen Pruni Armeniacae added to (10+8 times) boiling water decocted for2+2hours.CONCLUSION This optimal technique is stable and workable and can be used in industrial production.