摘要
血管平滑肌细胞增殖在高血压、动脉粥样硬化、再狭窄等心血管疾病的发生、发展中起着重要的作用。本文对血管平滑肌细胞胞外调控因素、胞内信号传导、细胞周期的研究现状及基于此三方面的药物研发进行综述。
The proliferation of vascular smooth muscle cells plays an important role in the initiation and aggravation in cardiovascular diseases such as hypertension, arteriosclerosis, restenosis. This article reviewed the progress in the studies on extracellular influencing factors, intracellular signal transduction, cell cycle of vascular smooth muscle cells and the relative drug research and development.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2004年第8期845-850,共6页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
血管平滑肌细胞
增殖
信号传导
细胞周
期:药物开发
vascular smooth muscle cell
proliferation
signal transduction
cell cycle
drug research and development