摘要
儿童用药不同于成人 ,随着年龄增长身体的发育会影响药物的吸收、分布、代谢及清除等许多方面 ,从而影响药物的药代动力学。儿童的用药量及用药间隔随年龄增长而有所变化 ,临床上儿童用药应当制订与年龄相适应的最佳方案 ,而不是简单的按体重或年龄给药。
Infants and children are far from adults in terms of medications. The growth and developmental changes profoundly affect the absorption, distribution and metabolism of drugs and the response to medications. The dosage and interval of drugs change along with growth and development, so it is needed those age-dependent adjustments in infants and children.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2004年第8期859-862,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
儿童
生长发育
药代动力学
药物代谢
children
growth and development
drug metabolism
pharmacodynamics