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RNAi相关技术及其在肿瘤基因治疗中的应用 被引量:2

RNAi technology and its application in tumor gene therapy
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摘要 RNA干扰 (RNAi)是由双链RNA(dsRNA)介导的、序列特异地引起转录后基因沉默的现象 ,是生物体内抵御转座子和病毒感染的重要保护机制之一。RNAi相关技术可作为一种简单有效的代替基因敲除的工具应用于功能基因组学和疾病的基因治疗研究。现综述RNAi机制、研究现状及RNAi相关技术在肿瘤基因治疗研究中的应用进展。
作者 叶景佳 曹江
出处 《国外医学(肿瘤学分册)》 2004年第9期670-674,共5页 Foreign Medical Sciences (Cancer Section)
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