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系统性红斑狼疮心脏损害及其相关因素分析 被引量:2

Analysis of cardiac injury and its underlying factors of systemic lupus erythematosus in children
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摘要 目的 探讨系统性红斑狼疮 (SLE)并心脏损害的特点及相关因素。方法 对 78例SLE患儿进行回顾性分析 ,并分为并心脏损害组 (40例 )与无心脏损害组 (38例 )。结果 SLE患儿并心脏损害占 5 1.3% ,最常见为心包积液 ,占 33.3% ;其次心肌炎 ,占 2 1.8% ;肺动脉高压占 12 .8%。SLE并心脏损害组与无心脏损害组在发热、高血压、肾功能不全、高滴度ANA、抗DNA阳性及低补体C3 方面均有显著差异 (P均 <0 .0 5 ) ,并得出其线性关系 :^ Y=- 8.4 32 +0 .2 5 9T +0 .2 1BUN +5 .3× 10 -5ANA +1× 10 -4DNA - 0 .137C3 ,r =0 .76 2。结论 SLE心脏损害是与否发热、高血压、肾功能不全、高滴度ANA、抗DNA阳性及低补体C3 有关 。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2004年第9期760-761,共2页 Journal of Applied Clinical Pediatrics
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  • 1张冬青,赵丹风,周光炎,张晓,陈顺乐,王益,高奇蓉,吴直江.人体T细胞CD_8^+VV^+亚群在活动性SLE患者中显示反抑制活性[J].中国免疫学杂志,1993,9(3):173-177. 被引量:15
  • 2Katz JK,Senecal JL,Rivest C,et al.A simple severity of disease index for sytemic lupus erythematosus[].Lupus.1993
  • 3Nived O,Sturfelt G,Wollheim F,et al.Systemic lupus erythematosus and infection: a controlled and prospective study including an epidemiological group[].Quarterly Journal of Medicine.1985
  • 4Futrell N,Millikan C.Frquency, etiology, and prevention of stroke in patients with systemic lupus erythematosus[].Stroke.1989
  • 5Roldan CA,Shively BK,Lau CC,et al.Systemic lupus erythematosus valve disease by transesophageal echocardiography and the role of antiphospholipid antibodies[].Journal of the American College of Cardiology.1992
  • 6Piliero P,Furie R.Functional asplenia in systemic lupus erythematosus[].Seminars in Arthritis and Rheumatism.1990

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  • 1王梅英,张源潮,张维,赵传艳.系统性红斑狼疮患者抗心肌抗体与心脏病变的相关性研究[J].中国实用内科杂志,2007,27(11):855-856. 被引量:3
  • 2菲尔斯坦.凯利风湿病学[M].粟占国,唐福林,译.北京:北京大学医学出版社,2010:1188-1189.
  • 3American College of Rheumatology ; 2009. The 1997 update of the 1982 American College of Rheumatology revised criteria for classification of systemic lupus erythematosus [ S ]. Available at:http://www, zhshen, com. cn/Article/Up- loadFiles/200908/2009080713115993, pdf. Accessed .lanuarv 29.2012.
  • 4World Health Organization monitoring of trends and determinants in cardiovascular disease (MONICA project) and manual of operation [ M ]. Cambridge, Harvard Unit, Geneva, 1 983.
  • 5Cervera R, Khamashta MA, Font J, et al. Mor- bidity and mortality in systemic lupus erythe- matosus during a 5 - year period. A multi- center prospective study of 1,000 patients. Eu- ropean Working Party on Systemic Lupus Et),- thematosus [ J ]. Medicine (Baltimore) , 1999, 78(3) :167 - 175.
  • 6Tseng ,I C, Lu L Y, Hu R J, et al. Elevated serum anti- endothelial cell autoantibodies titer is associated with lupus nephdtis in patients with systemic lupus erythematosus [J]. J Microhiol Immunol Infect, 2007,40( 1 ) :50-55.
  • 7Sasaki T, Muryoi T, Hatakeyama A, et al. Circulating anti-DNA immune complexes in active lupus nephritis [J]. Am J ned, 1991,91(4):355-362.
  • 8Napirei M, Karsunky H, Zevnik B, et al. Features of systemic lupus erythematosus in I)nasel-deficient mice [J]. Nat Genet, 2000,25(2) :177-181.
  • 9Su Y J, Cheng T T, Chen C J, et al. The association a- mong leukocyte apoptosis, autoantibodies and disease se- verity in systemic lupus erythematosus[ J]. J Transl Med, 2013,11(1) :261.
  • 10Kuenkele S, Beyer T D, Voll R E, et al. Impaired clear- ance of apoptotic cells in systemic lupus erythematosus: challenge of T and B cell tolerance [ J ]. Curr Rheumatol Rep, 2003,5(3) :175-177.

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