期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

实时荧光定量PCR分析脐血T细胞亚群中TRECs水平 被引量：4

Detection of TRECs level in cord blood T cells using fluorescent real-time quantitative PCR
下载PDF
导出
作者 李扬秋 杨力建 陈少华 韩素芳 周羽竝 陈青山
机构地区 暨南大学医学院血液病研究所 暨南大学医学院生化教研室 暨南大学医学院流行病学教研室
出处 《免疫学杂志》 CAS CSCD 北大核心 2004年第5期407-407,409,共2页 Immunological Journal
基金 国家自然科学基金(30270579) 国家教育部科技重点项目[教技司(2001)235号01091] 广东省自然科学基金重点项目(23001) 广东省教育厅"千百十工程"优秀人才培养基金项目(Q校02022) 广州市科委科技攻关项目(2001Z037013)资助
关键词 实时荧光定量PCR 脐血 T细胞亚群 TRECS 胸腺细胞 外周血
分类号 R392 [医药卫生—免疫学]
  • 相关文献

参考文献4

  • 1[1]AL-Harthi L, Marchetti G, Steffens CM, et al. Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reactionenzyme linked immunosorbent assay (PCR-ELISA) [ J ]. J Immunol Med, 2000, 237(1/2):187- 197.
  • 2李扬秋,杨力建,陈少华,陈嘉愉,刘薇薇,王震,张玉平,吴秀丽.实时定量PCR检测正常人外周血T细胞和胸腺细胞中sjTRECs水平[J].现代临床医学生物工程学杂志,2001,7(6):397-400. 被引量：37
  • 3[3]Malphettes M, Carcelain G, Saint-Mezard P, et al. Evidence for naive T-cell repopulation despite thymus irradiation after autologous transplantation in adults with multiple myeloma:role of ex vivo CD34 + selection and age[ J]. Blood, 2003,101(5):1 891- 1 897.
  • 4李扬秋,杨力建,陈少华,韩素芳,张学利,许敏华.TCR Dβ-Jβ sjTRECs检测方法的建立和应用[J].免疫学杂志,2003,19(6):467-470. 被引量：12

二级参考文献18

  • 1A1 Harthi L, Marchetti G, Steffens CM, et al. Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELIgA) [ J ]. J Immunol Med, 2000, 237(1 - 2) :187 - 197.
  • 2Douek DC, McFarland RD, Keiser PH, et al. Changes in thymic function with age and during the treatment of HIV infection[J]. Nature, 1998, 396(6 712) :690 - 695.
  • 3Hatzakis A, Touloumi G, Kaxanicolas R, et al. Effect of recent thymic emigrants on progression of HIV-1 disease[J].Lancet, 2000, 355(9 204):599-604.
  • 4Rowen L, Koop BF, Hood L. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus[Jl.Science, 1996, 272(5 269) : 1 755 - 1 762.
  • 5Lewis SM, Wu GE. The origins of V(D)J recombination[J].Cell, 1997, 88(2):159- 162.
  • 6Hazenberg Md, Otto SA, Cohen Stuart JW, et al. Increased cell division but not thymic dysfunction rapidly affects the T- cell receptor excision circle content of the naive T cell population in HIV-1 infection[Jl. Nat Med, 2000, 6(8) : 1 036 -1 042.
  • 7Lewin SR, Heller G, Zhang L, et d. Direct evidence for new T-cell generation by patients after either T-cell-depleted or unmodified allogeneic hematopoietic stem cell transplantations[J]. Blood, 2002, 100(6):2235-2242.
  • 8Douek DC,Vescio RA,Betts MR,et al.Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T cell reconstitution[].The Lancet.2000
  • 9Ichihara Y,Hirai M and Kurosawa Y.Sequence and chromosome assignment to 11p13-p12 of human RAG genes[].Immunology Letters.1992
  • 10AL-Harthi L,Marchetti G,Steffens GM.Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction - enzyme linked immunosorbent assay (PCR-ELISA)[].Journal of Immunological Methods.2000

共引文献43

同被引文献42

  • 1李扬秋,刘启发.血液肿瘤靶向治疗和免疫治疗[J].肿瘤防治研究,2004,31(6). 被引量：5
  • 2李扬秋,陈少华,杨力建,陈青山.实时定量PCR检测白血病中BCL11B基因的表达水平[J].免疫学杂志,2006,22(4):463-465. 被引量：4
  • 3PRZYBYLSKI G K, DIK W A, WANZECK J, et al. Disruption of the BCL11B gene through inv (14) (q11. 2q32. 31) results in the expression ofBCLllB TRDC fusion transcripts and is associated with the absence of wild2type BCL11B transcripts in T-ALL [J]. Leukemia, 2005, 19(2) : 201 -208.
  • 4BEZROOKOVE V, VAN ZELDEREN BHOLA S L, BRINK A, et al. A novel t (6 ; 14) ( q252q27 ; q32) in acute myelocytic leukemia involves the BCLllB gene [J]. Cancer Genet Cytogenet, 2004, 149(1) : 72 -76.
  • 5GRABARCZYK P, PRZYBYLSKI G K, DEPKE M, et al. Inhibition of BCLllB expression leads to apoptosis of malignant but not normal mature T cells. Oncogene, 2007, (26) : 3797 -3810.
  • 6WAKABAYASHI Y, WATANABE H, INOUE J, et al. BCL11B is required for differentiation and survival of alphabeta T lymphocytes [J]. Nat Immunol, 2003,4(6) : 533 - 539.
  • 7PRZYBYLSKI G K, DIK W A, WANZECK J, et al. Disruption of the BCL11Bgene through inv(14) (q11. 2q32.31 ) results in the expression of BCLIIB TRDC fu- sion transcripts and is associated with the absence of wild- type BCL11B transcripts in T-ALL[J]. Leukemia, 2005, 19(2) :201.
  • 8KAN Z, ROUCHKA E C, GISH W R, et al. Gene structure prediction and alternative splicing analysis using genomically aligned ESTs. [ J ]. Genome Res, 2001, 11 (5) : 889 -900.
  • 9MODREK B, RESCH A, GRASSO C, et al. Genome wide detection of alternative splicing in expressed sequences of human genes [J]. Nucleic Acids Res, 2001, 29(13) : 2850 -2859.
  • 10Przybylski OK, Dik WA, Wanzeck J, et al. Disruption of the BCL11B gene through inv (14) (q11. 2q32. 31 ) results in the expression of BCL11BTRDC fusion transcripts and is associated with the absence of wild2type BCL11B transcripts in TALL [J], Leukemia, 2005, 19 (2) :201-208.

引证文献4

二级引证文献7

免疫学杂志
2004年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部