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大鼠脊髓前角神经元内维生素D依赖性钙结合蛋白与小白蛋白共存 被引量：1

Co-existence of calbindin-D28k with parvalbumin in neurons of spinal cord anterior horn in rats
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摘要 目的 :观察大鼠脊髓前角神经元内维生素D依赖性钙结合蛋白 (CB)与小白蛋白 (PV)的共存情况 .方法 :免疫荧光组织化学双重标记技术 .结果 :脊髓前角内的部分中、小型神经元呈CB或PV阳性 ;绝大部分CB阳性的前角神经元亦呈PV阳性 ,即CB与PV共存于这些神经元 .结论 :CB与PV共存于部分前角神经元 ,这些神经元可能为Renshaw细胞并参与对前角α运动神经元的反馈抑制调控 . AIM: To observe the co-existence of calbindin-D28k (CB) with parvalbumin (PV) in neurons of the anterior horn of the spinal cord in rats. METHODS: Immunofluorescence histochemical double-staining method was used. RESULTS: Some of the medium and small-sized neurons in the anterior horn of the spinal cord showed CB- or PV-immunopositive staining. The majority of the CB-immunoreactive neurons also exhibited PV-immunoreactivities, i.e. CB and PV co-existed in these neurons. CONCLUSION: CB and PV co-exist in some of the neurons in the anterior horn. CB/PV double-labeled neurons might belong to Renshaw cells and they may have some feed-back inhibitory regulatory effects on the activities of α motor neurons in the anterior horn.
作者 陶发胜 李辉 李云庆
机构地区 乌鲁木齐军医学院解剖学教研室 第四军医大学基础部解剖学教研室
出处 《第四军医大学学报》 北大核心 2004年第18期1645-1647,共3页 Journal of the Fourth Military Medical University
基金 国家自然科学基金资助项目 (30 370 4 58)
关键词 脊髓 前角 钙结合蛋白质 维生素D依赖性 小白蛋白 Renshaw细胞 spinal cord anterior horn calcium-binding prtein, vitamin D-dependent parvalbumins Renshaw cell
分类号 R322.81 [医药卫生—人体解剖和组织胚胎学]
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参考文献9

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二级参考文献6

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共引文献3

同被引文献9

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第四军医大学学报
2004年 第18期

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